DEVELOPMENT AND VALIDATION OF REVERSED PHASE HPLC METHOD FOR ESTIMATION OF SIMVASTATIN IN PHARMACEUTICAL DOSAGE FORM
نویسندگان
چکیده
منابع مشابه
Development and Validation of Reversed Phase Hplc Method for Estimation of Ceftriaxone in Pharmaceutical Dosage Form
Ceftriaxone sodium (Figure 1) is chemically (6R,7R)-7[[(2Z)-(2-amino-4thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3[[(1,2,5,6-tetrahydro-2-methyl-5,6-ioxo-1,2,4-triazin3-yl)thio]-methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene2-carboxylic acid 1 . Ceftriaxone is a third generation, semisynthetic cephalosporin antibiotic. Cephalosporins are derivatives of 7aminocephalosporic acid and are closely rel...
متن کاملDevelopment and Validation of a Reversed-phase HPLC Method for Assay of the Decapeptide Cetrorelix Acetate in Bulk and Pharmaceutical Dosage Forms
A gradient reversed-phase high performance liquid chromatography (HPLC) method was developed for the assay of cetrorelix acetate, a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity used in infertility treatment. The HPLC method, which is used to determine cetrorelix in bulk and pharmaceutical dosage forms, was validated per ICH guidelines. The chromatograph...
متن کاملDevelopment and Validation of a Reversed-phase HPLC Method for Assay of the Decapeptide Cetrorelix Acetate in Bulk and Pharmaceutical Dosage Forms
A gradient reversed-phase high performance liquid chromatography (HPLC) method was developed for the assay of cetrorelix acetate, a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity used in infertility treatment. The HPLC method, which is used to determine cetrorelix in bulk and pharmaceutical dosage forms, was validated per ICH guidelines. The chromatograph...
متن کاملDevelopment and Validation of Reversed-Phase HPLC Method for Simultaneous Estimation of Rosuvastatin and Fenofibrate in Tablet Dosage Form
A simple, precise and accurate reversed-phase liquid chromatographic method has been developed for the simultaneous estimation of Rosuvastatin and Fenofibrate in tablet formulations. The chromatographic separation was achieved on (Inertsil ODS, 250 x 4.6mm, 5μ column) analytical column. And mobile phase as mixture of Water (pH adjusted to 2.5 with ortho phosphoric acid) and acetonitrile in rati...
متن کاملSimultaneous RP-HPLC and UV Spectroscopic Method Development and Validation for Estimation of Ibandronate Sodium in Bulk and Pharmaceutical Dosage Form
The present study describes a simple, accurate, precise and cost effective UV-Vis Spectroscopic and RP-HPLC method for the estimation of Ibandronate sodium (IBN). The determination of Ibandronate sodium (IBN) was performed by both UV and RP-HPLC method using 215 nm as the determination wavelength. The drug was dissolved in NaOH solution (0.1N NaOH) for estimation in UV and in distilled water fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2012
ISSN: 2250-1177
DOI: 10.22270/jddt.v2i3.133